Currently, there is no way to check the size before picking the file up. It would be best to write a custom script that filters out the files.
If the receiving side can accept a full sized web service call like that, we have a new feature to call a REST web service with an output stream, this would allow you to create your payload using file streams, then push the entire payload to the receiving system using streams. This allows you to handle large files without needing to read them up into memory.