This is caused by a truststore that is not found in the qie service manager.
The fix is to remove the following arguments in the QIE service manager startup tab:
-Djavax.net.ssl.trustStore=/some/loc/on/server/ mytruststore.jks
-Djavax.net.ssl.trustStorePassword=changeit

Once removed stop and start QIE
NOTE: The javax.net.ssl.trustStore and javax.net.ssl.trustStorePassword JVM arguments have been deprecated and should NOT be used with the QIE environment. All certificate management is handled through QIE's Certificates Management page in the QIE Console.